Comparación de los niveles de hormonas tiroideas entre dos líneas de pollo de engorde

Abstract

Objective: to establish reference values for TSH and free T₄ in two lines of broilers (Ross and Cobb), and also to compare the thyroid hormone levels in serum of those two lines.  Materials and methods: after fasting, serum of one-hundred, 35 days of age broilers (50 Ross and 50 Cobb) was obtained, and TSH and free T₄ levels were measured using enzymatic immunoassay.  Results: the TSH values for the Ross line (µUI/mL) were: average 0.00; minimum 0.06; maximum 0.34; and 0.07 standard deviation. For the Cobb line (µUI/mL) the values were: average 0.01; minimum 0.08; maximum 0.42; and 0.09, standard deviation. The P value for the F test is superior or the same as 0.05. As a consequence, there is no statistically significant difference with a confidence level of 95 %. for TSH between the two analyzed lines The free T₄ values for the Ross (ng/dL) line were: average 0.71; minimum 0.60; maximum 1.15; and 0.27 standard deviation, and the values found for the Cobb line were: average 0.76; minimum 0.20; maximum 1.26; and 0.28 standard deviation. The P value for the F test is superior or the same as 0.05. As a consequence there is no statistically significant difference with a confidence level of 95 %. for free T₄ between the two analyzed lines.  Conclusion: levels of TSH and free T₄ are similar for the two lines tested, which can be attributed to a similar hormonal response they have due to the genetic selection they have undergone. Reference values for TSH and free T₄ are presented.

Keywords:

metabolismo

pollo de engorde

TSH

T4L

metabolism

broilers

TSH

free T4

References

Anne Mcnabb FM. Sturkie’s avian physiology. 5 ed. USA: Academic press; 1999. p. 455-10.

Győrffy A, Sayed-Ahmed A, Zsarnovszky A, Frenyó Vl, Decuypere E, Bartha T. Effects of energy restriction on thyroid hormone metabolism in chickens. Acta Vet Hungarica 2009; 57(2):319-11.

Dickson WM, Feldman EC, Hedge GA, Martin R, McDonald LE. Fisiología veterinaria cunningham. In: Cunningham JG, eds. Las glándulas endocrinas y su función. 3 ed. Madrid: Elsevier España S.A; 2003. p. 342-42.

Banks WJ. Histología veterinaria aplicada. 1 ed. Ciudad de México: el manual moderno SA de C.V. 1986. p. 583-8.

Lumeij JT. Avian medicine: principles and application. In: Ritchie BW, Harrison GJ, Harrison LR, eds. Endocrinology wingers pub. Lake Worth, Florida; 1994.

Reyns GE, Janssens KA, Buyseb J, Kühn ER, Darras VM. Changes in thyroid hormone levels in chicken liver during fasting and refeeding. Comparative Biochemistry and Physiology 2002; 132:239-6.

Decuypere E, Van Asa P, Van der Geyten S, Darras VM. Thyroid hormone availability and activity in avian species: A review. Domestic Animal Endocrinology 2005; 29:63-14.

Sandoval GL, Terraes JC, Esquivel de Luchi GP, Revidatti FA, Fernández RJ, Sotelo NS, Maruñak SL. Hormonas tiroideas, inmovilidad tónica, peso vivo y eficiencia alimenticia en pollos criados en temporadas estival e invernal de zona subtropical, con hacinamiento e inversión corporal. Comunicaciones Científicas y Tecnológicas 2004.

Darras VM, Van der Geyten S, Kühn ER. Thyroid hormone metabolism in poultry. Biotechnol. Agron. Soc. Environ 2000; 4:13-20.

Scanes CG. Perspectives on the endocrinology of poultry growth and metabolism. General and Comparative Endocrinology 2009; 163:24-32.

Julian RJ. Production and growth related disorders and other metabolic diseases of poultry: A review. The Veterinary Journal 2005; 169:350-19.

Silva JE. The thermogenic effect of thyroid hormone and its clinical implications. Annals of Internal Medicine 2003; 139:205-8.

Tao X, Zhang ZY, Dong H, Zhang H, Xin H. Responses of thyroid hormones of market-size broilers to thermoneutral constant and warm cyclic temperatures. Poult Sci 2006; 85:1520-8.

Chiang W, Booren A, Strasburg G. The effect of heat stress on thyroid hormone response and meat quality in turkeys of two genetic lines. Meat Science 2008; 80:615-7.

Macwhirter P, Avian Medicine: principles and application. In: Ritchie BW, Harrison GJ, Harrison LR, eds. Malnutrition wingers pub. Lake Worth, Florida. 1994. p. 859.

Keagy EM, Carew LB, Alster FA, Tyzbir RS. Thyroid function, energy balance, body composition and organ growth in protein-deficient chicks. J. Nutr 1987; 117:1532-8.

Carew LB, Alster FA. Dietary carbohydrate and fat do not alter the thyroid response to protein deficiency in chicks (Abstract). Proc Soc Exp Biol Med 1997; 215(1):82-6.

Hutchins MO. Newcomer WS. Metabolism and excretion of thyroxine and triiodothyronine in chickens (Abstract). General and Comparative Endocrinology 1966; 6(2):239-9.

Rosebrough RW. Dietary protein levels and the responses of broilers to single or repeated cycles of fasting and refeeding. Nutrition Research 2000; 20(69):877-9.

Geris KL, Berghman LR, Kühn ER, Darras VM. The drop in plasma thyrotropin concentrations in fasted chickens is caused by an action at the level of the hypothalamus: role of corticosterone. Domestic Animal Endocrinology 1999; 16(4):231-6.

Hudelson KS, Hudelson P. Endocrine considerations. In: Clinical avian medicine Harrison G.J. Lightfoot T.L, eds. internet publisher: international veterinary information service, Ithaca NY; 2009.

Lauterio TJ, Scanes CG. Hormonal responses to protein restriction in two strains of chickens with different growth characteristics. J. Nutr. 1987; 117:758-5.

Piestun Y, Shinder D, Ruzal M, Halevy O, Yahav S. The effect of thermal manipulations during the development of the thyroid and adrenal axes on in-hatch and post-hatch thermoregulation. Journal of Thermal Biology 2008; 33:413-5.

Hulbert AJ.Thyroid hormones and their effects: a new perspective. Biol. Rev. 2000; 75:519-112.

Ferrini G, Manzanilla EG, Menoyo D, Esteve-Garcia E, Baucells MD, Barroeta AC. Effects of dietary n-3 fatty acids in fat metabolism and thyroid hormone levels when compared to dietary saturated fatty acids in chickens. Livestock Science 2010; 131:287-4.

Tona K, Onagbesan OM, Jego Y, Kamers B, Decuypere E, Bruggeman V. Comparison of embryo physiological parameters during incubation, chick quality, and growth performance of three lines of broiler breeders differing in genetic composition and growth rate. Poult Sci 2004; 83(3):507-6.

Davis GS, Anderson KE, Carroll AS. The effects of long-term caging and molt of Single Comb White Leghorn hens on heterophil to lymphocyte ratios, corticosterone and thyroid hormones. Poult Sci 2000; 79(4): 514-4.

Druyan S. The effects of genetic line (broilers vs. layers) on embryo development. Poult Sci 2010; 89:1544-4.

Lien RJ, Siopes TD Effects of short-term thyroxine administration during the laying period on egg production and moulting by Turkeys. Brit Poult Sci 1993; 34(2):405-416.

Lien RJ, Siopes TD. Effects of thyroidectomy on egg production, molt, and plasma thyroid hormone concentrations of turkey hens. Poult Sci 1989; 68(8):1126-32.