DOI: 10.17151/biosa.2018.17.1.3
Cómo citar
Aguillón Osma J., Bedoya Blandón Ángela M., Loango Chamorro N., & Landázuri P. (2018). Niveles de estradiol en niños y jóvenes y su relación con género, edad, presión arterial, lípidos plasmáticos y polimorfismo XbaI del receptor de estrógenos. Biosalud, 17(1), 19-30. https://doi.org/10.17151/biosa.2018.17.1.3

Autores/as

Johanny Aguillón Osma

M MSc. Bioquímica. Programa Lic. en Biología, Facultad de Educación, Universidad del Quindío. Armenia, Colombia.

Universidad del Quindío
jaguillon@uniquindio.edu.co
https://orcid.org/0000-0002-1041-1140
Ángela María Bedoya Blandón

Bióloga. Programa de Biología, Facultad Ciencias Básicas y Tecnológicas, Universidad del Quindío. Armenia, Colombia.

Universidad del Quindío
angelamariabedoya26@gmail.com
https://orcid.org/0000-0002-9016-2454
Nelsy Loango Chamorro

PhD. Biotecnología. Programa de Biología, Facultad de Ciencias Básicas y Tecnológicas, Universidad del Quindío. Armenia, Colombia.

Universidad del Quindío
neloango@uniquindio.edu.co
https://orcid.org/0000-0002-4777-3647
Patricia Landázuri

PhD. Bioquímica. Programa de Medicina, Facultad de Ciencias de la Salud, Universidad del Quindío. Armenia, Colombia.

Universidad del Quindío
plandazu@uniquindio.edu.co
https://orcid.org/0000-0002-6893-1405

Resumen

La identificación de factores de riesgo para las enfermedades cardiovasculares (ECV) puede ayudar a prevenir su desarrollo. Las hormonas esteroides a través de sus receptores y las variaciones genéticas influyen sobre el metabolismo de los lípidos y la presión arterial, entre otras funciones. Métodos: Estudio descriptivo realizado en niños y adolescentes entre 8 y 18 años de edad. Objetivo: Determinar los niveles de estradiol y su relación con género, edad, presión arterial, lípidos plasmáticos y polimorfismo XbaI del receptor de estrógenos. Resultados: No se encontró relación estadística entre el polimorfismo XbaI y las concentraciones de estradiol, pero sí entre el polimorfismo y el perfil lipídico, de igual manera entre las concentraciones de esta hormona con triglicéridos y c-VLDL. Conclusión: Este trabajo evidencia la relación entre niveles de estrógenos, edad, presión sanguínea y lípidos plasmáticos, de igual forma demuestra una relación entre polimorfismo XbaI del ESR1 y los niveles de lípidos.

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