Comparación del efecto antihelmíntico de dos especies botánicas usadas tradicionalmente en comunidades afrovenezolanas. Considerando perspectiva etnofarmacológica

Abstract

Afro-Venezuelan communities in Miranda State use ethnomedical protocols as therapeutic alternatives for cases of gastrointestinal parasites with different degrees of complication, using various botanical species with a high Number of Significant Uses. Two of these species, with certain differences in the traditional prescription, but with the same NUS for gastrointestinal parasitosis, such as Justicia pectoralis Jacq. (Acanthaceae) and Capraria biflora L. (Scrophulariaceae), were evaluated showing the effect of their aqueous extracts on the in vitro mobility pattern of Strongyloides stercoralis larvae in nutrient agar plates. Three concentrations of each extract were tested (low, medium and high), according to reported toxicity, and included negative and therapeutic control (Ivermectin). The J. pectoralis extract showed a significant decrease in larval mobility, and the C. biflora extract did not show any changes related to the negative control. Results of both species are compared, considering both experimental and cultural aspects in the preliminary ethnopharmacological validation.

Keywords

ethnopharmacology

gastrointestinal parasite diseases

Justicia pectoralis Jacq.

Capraria biflora L.

afrovenezuelan community

medicinal plants

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