Valoración in vitro de Bocconia frutescens L. contra Trichophyton rubrum. Comprobando la medicina tradicional.

Abstract

Trichophyton rubrum is the main cause of dermatomycoses. Synthetic drugs which have side effects and present a variable effectiveness have been used for treatment of this fungus. Bocconia frutescens extracts are used in folk medicine to treat almost all problems of infectious dermatitis. This study shows in vitro antifungal evaluation of 3 parts of the plant species of Bocconia frutescens leaf, stem and seed, versus Trichophyton rubrum strains pathogenic for humans. Extracts of each plant part were obtained by Soxhlet extraction using 95% ethanol as solvent; for the preparation of agar PDA agar was used; the fungus was inoculated in the middle of each petri dish to measure the diameter growth during 15 days. A Kruskal-Wallis test was performed, multifactor ANOVA analysis was made, and Tukey test and determination of the DL50 and DL100 were carried out. It was found that T. rubrum is susceptible in vitro to the three B. frutescens extracts, the action of the stem is different from that of the leaf, the stem is different from the seed and the leaf is equal to the seed. These results allow proposing this species as a potential source of antifungal compounds and must be subject to new bioassays and phytochemical studies to obtain the percentage of phytochemical components of each part of the plant.

Keywords:

T. rubrum

B. frutescens

medicina tradicional

dosis mínimas

T. rubrum

B. frutescens

traditional medicine

small doses

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