PDF
FLIP
Fecha Publicación: 2008-06-20
Cómo citar
Uribe Velásquez, L. F. ., Lenz Souza, M. I. ., & Henry Osorio, J. . (2008). Origem e características do folículo pré ovulatório depois de luteólise induzida em diferentes estágios da fase luteal do ciclo estral em ovelhas. Revista Veterinaria Y Zootecnia (On Line), 2(1), 32–41. Recuperado a partir de https://revistasojs.ucaldas.edu.co/index.php/vetzootec/article/view/5744
Más formatos de cita
Autores/as
Resumen
RESUMO: Avaliou-se a resposta ovariana, usando ultrassonografia transretal, pós aplicação de duas injeções de prostaglandina (PGF2α) em diferentes intervalos. Utilizaram-se 14 fêmeas durante a estação reprodutiva, sendo que todas receberam uma dose intramuscular de um análogo de PGF2α. As ovelhas foram distribuídas em dois grupos (n = 7), aos quais administrou-se PGF2α sete dias (PG7) ou nove dias (PG9) após ovulação (quando o folículo dominante da onda dois encontrava-se na fase de crescimento ou platô, respectivamente). Examinaram-se os ovários diariamente, utilizando-se um ultrassom Aloka 500, provido de um transdutor linear transretal de 7,5 MHz. A ultrassonografia iniciou-se um dia antes da segunda aplicação de PG até o decimo dia 10 depois da ovulação, para os dois grupos. Amostras de sangue foram colhidas, via punção jugular, a cada dia, para a quantificação de progesterona. As concentrações plasmáticas de progesterona mostraram-se menores no PG7 quando comparado com o PG9, imediatamente antes do tratamento com a PGF2α (4,10±0,17 vs 4,91±0,29 ng/mL, respectivamente; P<0.05). A média do diâmetro máximo atingido pelo folículo dominante da onda dois foi maior no grupo tratado PG7 comparado com o PG9 (5,5±0,19 vs 4,29±0,26 mm; P<0,05). A quantidade de folículos pequenos (2-2,5 mm) foi maior (4,57±0,78 versus 8,42±1,36) no dia seis, nos grupos PG7 e PG9, respectivamente, enquanto não foram observadas mudanças nos folículos médios. A proporção de folículos grandes (4 mm) incrementou-se depois da luteólise; os valores foram menores nas ovelhas tratadas no PG7, enquanto mantiveram-se estáveis no tempo no PG9. Em conclusão, nas ovelhas com rápida e completa luteólise, a ovulação ocorreu do folículo dominante da onda dois, em fêmeas tratadas nos dias sete ou nove após a ovulação.
Palabras clave:
Citas
Ali, A. Effect of time of eCG administration on follicular response and reproductive performance of FGA-treated Ossimi ewes. Small Ruminant Research, v.72, p.33-37, 2007.
Amorim, E.A.M.; Torres, C.A.A.; Amorim, L.S. et al. Dinâmica follicular em cabras da raca Toggenburg em lactação tratadas ou não com somatotropina bovina recombinante. Arquivos Brasileiros de Medicina Veterinária e Zootecnia, v.59, p.1500- 1508, 2007.
Binelli, M.; Hampton, J.; Buhi, W.C. et al. Persistent dominant follicle alters pattern of oviductal secretory proteins from cows at estrus. Biology of Reproduction, v.61, p.127-134, 1999.
Campbell, B.K.; Mann, G.E.; McNeilly, A.S. et al. Pulsatile secretion of inhibin, oestradiol and androstenedione by the ovary of the sheep during the oestrus cycle. Journal Endocrinology, v.126, p.385-393, 1990.
Castonguay, F.; Dufour, J.J.; Minvielle, F. et al. Follicular dynamics and dominance in Boorola x Finnish Landrace and Boorola x Suffolk ewes heterozygous for the F gene. Journal Reproduction and Fertility, v.89, p.193-203, 1990.
Evans, A.C.; Flynn, J.D.; Quinn, K.M. et al. Ovulation of aged follicles does not affect embryo quality or fertility after a 14-day progestagen estrus synchronization protocol in ewes. Theriogenology, v.56, p.923-936, 2001.
Fabre, S.; Pierre, A.; Mulsant, P. et al. Regulation of ovulation rate in mammals: contribution of sheep genetic models. Reproductive Biology and Endocrinology, v.4, p.1-12, 2006.
GdeNicolo, S.T.; Morris, S.T.; Kenyon, P.R. et al. Induced seasonal reproductive performance in two breeds of sheep. Animal Reproduction Science, v.103, p.278-289, 2007.
Ginther, O.J.; Araujo, R.R.; Palhao, M.P. et al. Necessity of sequencial pulses of prostaglandin F2alpha for complete physiologic leteolysis in cattle. Biology of Reprouction, v.80, p.641-648, 2009.
Goel, A.K.; Agrawal, K.P. Oestrus synchronization in cyclic goats following lutalyse administration. Indian Journal of Animal Science, v.68, p.155- 156, 1998.
González de Bulnes, A.; Moreno, S.; Gómez-Brunet, A. et al. Follicular dynamic during the oestrous cycle in dairy goats. Animal Science, v.68, p.547- 554, 1999.
González de Bulnes, A.; Veiga-López, A.; García, P. et al. Effects of progestagens and prostaglandin analogues on ovarían function and embryo viability in sheep. Theriogenology, v.63, p.2523- 2534, 2005.
González-Añover, P.; Encinas, T.; Veiga-López, A. et al. Effects of bree don folicular dynamics and oestradiol secretion during the folicular phase in sheep. Reproduction Domestic Animal, v.42, p.29-33, 2007.
Goravanahally, M.P.; Sen, A.; Inskeep, E.K., et al. PKCepsilon and an increase in intracellular calcium concentration are necessary for PGF2alpha to inhibit LH-stimulated progesterone secretion in cultured bovine steroidogenic luteal cells. Reproductive Biology and Endocrinology, v.5, p.1-13, 2007.
Guido, S.I.; Oliveira, M.A L.; Lima, P.F. Eficiência do syncromate-B associado a P F2 sobre o restablecimento da ciclicidade de cabras Saanen em anestro lactacional. Revista Brasileira de Reproducción Animal, v.23, p.51-56, 1999.
Hackett, A.J.; Robertson, H.A. Effect of dose and time of injection of prostaglandin F 2α in cycling ewes. Theriogenology, v. 13, p.347-351, 1980.
Herrera, H.L.; Feldman, S.D.; Zarco, Q.L. et al. Evaluación del efecto luteolítico de la prostaglandina F2 alfa en diferentes días del ciclo estral de la borrega. Veterinaria México, v. 21, p.143-147, 1990.
Holtz, W.; Sohnrey, B.; Gerland, M., et al. Ovsynch synchronization and fixed-time insemination in goats. Theriogenology, v. 69, p.785-792, 2008.
Kridli, R.T.; Al-Khetlib, S.S. Reproductive responses in ewes treated with eCG or increasing doses of royal jelly. Animal Reproduction Science, v.92, p.75-85, 2006.
Lafrance, M.; Goff, A. K. Effect of pregnancy on oxytocin-induced release of prostaglandin F2a in heifers. Biology of Reproduction, v.3, p.1113– 1119, 1985.
Latour, D.; Littell, R. Advanced general linear models with an emphasis on mixed models. Version 6.12. Cary: SAS Institute, 1996. 268p.
Leyva, V.; Buckrell, B.C.; WALTON, J.S. Regulation of follicular and ovulation in ewes by exogenous progestagen. Theriogenology, v.50, p.395-416, 1998.
Liu, X.; Dai, Q.; Hart, E.J. et al. Ultrasonographic characteristics of ovulatory follicles and associated endocrine changes in cyclic ewes treated with medroxyprogesterone acetate (MAP)-releasing intravaginal sponges and equine chorionic gonadotrophin (eCG). Reproduction Domestic Animals, v.42, p.393-401, 2007.
López-Sebastian, A.; González-Bulnes, A.; Carrizosa, J.A. et al. New estrus synchronization and artificial insemination protocol for goats based on male exposure, progesterone and cloprostenol during the non-breeding season. Theriogenology, v.68, p.1081-1087, 2007.
Lucy, M.C.; Savio, J.D.; Badinga, L. et al. Factors that affect ovarian follicular dynamics in cattle. Journal of Animal Science, v.70, p.3615-3626, 1992.
McGinley, R.; Casey, J. H. Analysis of progesterone in unextrated serum; a method using danazol (17 a-preg-4-en-20-yno (2,3) isoxasol-17-ol) a bloker of steroid binding to proteins. Steroids, v.33, p.127-138, 1979.
McNeilly, A.S.; Picton, H.M.; Campbell, B.K. et al. Gonadotrofic control of follicle growth in the ewe. Journal of Reproduction and Fertility, v.43, p.177-186, 1991.
Menchaca, A.& Rubianes, E. Efecto of high progesterone concentrations during the early luteal phase in the lenght of the ovulatory cycle of gotas. Animal Reproduction Science, v.68, p.69-76, 2001.
Menchaca, A. & Rubianes, E. Relation between progesterone concentrations during the early luteal phase and follicular dynamic in goats. Theriogenology, v.57, p.1411-1419, 2002.
Menchaca, A.; Miller, V.; Salveraglio, V. et al. Endocrine, luteal and folicular responses after the use of the short-term protocol to synchronize ovulation in goats. Animal Reproduction Science, v.102, p.76-87, 2007.
Mihm, M.; Curran, N.; Hyttel, P. et al. Effect of dominant follicle persistence on follicular fluid estradiol and inhibin and on oocyte maturation in heifers. Journal of Reproduction and Fertility, v.116, p.293-304, 1999.
Pierson, R.A.; Ginther, J.O. Follicular population during the oestrous cycle in heifers. I – Influence of day. Animal Reproduction Science, v.14, p.165-176, 1987.
Quirk, S.M.; Quirk, G.J.; Hickey, J.E. et al. Growth and regression of ovarian follicles during the follicular phase of the oestrous cycle in heifers undergoing spontaneous and PGF2α induced luteolysis. Journal Reproduction of Fertility, v.77, p.211-219, 1986.
Ravindra, J.P.; Rawlings, N.C.; Evans, A.C.O. et al. Ultrasonographic study of ovarian follicular dynamics in ewes during the estrous cycle. Journal Reproduction and Fertility, v.101, p.501-509, 1994.
Safdarian, M.; Kafi, M.; Hashemi, M. Reproductive performance of Karakul ewes following different oestrous synchronization treatments outside the natural breeding season. South African Journal of Animal Sciences, v.36, p.229-234, 2006.
Scaramuzzi, R.J.; Adams, N.R.; Baird, D.T. et al. A model for follicle selection and the determination of ovulation rate in the ewe. Reproduction Fertility Development, v.5, p.459-478, 1993.
Schrick, F.N.; Surface, R.A.; Pritchard, J.Y. et al. Ovarian structures during the estrous cycle and early pregnancy in ewes. Biology of Reproduction, v.49, p.1133-1140, 1993.
Uribe-Velásquez, L.F.; Oba, E.; Lara-Herrera, L.C.; et al. Respostas endócrinas e ovarianas associadas com o folículo dominante da primeira onda folicular em ovelhas sincronizadas com CIDR ou PGF2α. Revista Brasileira de Zootecnia, v.31, p.944-953, 2002.
Uribe-Velásquez, L.F.; Souza, M.I.L.; Loaiza, A.M.E. Efecto de la sincronización del estro con prostaglandina-f2α vs CIDR + 500 UI de eCG en ovejas Bergamacia durante el inicio de la fase luteal. Revista Científica, v.XVIII, p.368-373, 2008a.
Uribe-Velásquez, L.F.; Oba, E.; Souza, M.I.L. Población folicular y concentraciones plasmáticas de progesterona (P4) en ovejas sometidas a diferentes protocolos de sincronización. Archivos de Medicina Veterinaria, v.40, p.83-88, 2008b.
Uribe-Velásquez, L.F.; Oba, E.; Souza, M.I.L. Efeitos da progesterona exógena sobre o desenvolvimento folicular em ovelhas. Arquivos Brasileiros de Medicina Veterinária e Zootecnia, v.60, p.58- 65, 2008c.
Weems, C.W.; Weems, Y.S.; Randel, R.D. Prostaglandins and reproduction in female farm animals. The Veterinary Journal, v. 171, p.206- 228, 2006.
Amorim, E.A.M.; Torres, C.A.A.; Amorim, L.S. et al. Dinâmica follicular em cabras da raca Toggenburg em lactação tratadas ou não com somatotropina bovina recombinante. Arquivos Brasileiros de Medicina Veterinária e Zootecnia, v.59, p.1500- 1508, 2007.
Binelli, M.; Hampton, J.; Buhi, W.C. et al. Persistent dominant follicle alters pattern of oviductal secretory proteins from cows at estrus. Biology of Reproduction, v.61, p.127-134, 1999.
Campbell, B.K.; Mann, G.E.; McNeilly, A.S. et al. Pulsatile secretion of inhibin, oestradiol and androstenedione by the ovary of the sheep during the oestrus cycle. Journal Endocrinology, v.126, p.385-393, 1990.
Castonguay, F.; Dufour, J.J.; Minvielle, F. et al. Follicular dynamics and dominance in Boorola x Finnish Landrace and Boorola x Suffolk ewes heterozygous for the F gene. Journal Reproduction and Fertility, v.89, p.193-203, 1990.
Evans, A.C.; Flynn, J.D.; Quinn, K.M. et al. Ovulation of aged follicles does not affect embryo quality or fertility after a 14-day progestagen estrus synchronization protocol in ewes. Theriogenology, v.56, p.923-936, 2001.
Fabre, S.; Pierre, A.; Mulsant, P. et al. Regulation of ovulation rate in mammals: contribution of sheep genetic models. Reproductive Biology and Endocrinology, v.4, p.1-12, 2006.
GdeNicolo, S.T.; Morris, S.T.; Kenyon, P.R. et al. Induced seasonal reproductive performance in two breeds of sheep. Animal Reproduction Science, v.103, p.278-289, 2007.
Ginther, O.J.; Araujo, R.R.; Palhao, M.P. et al. Necessity of sequencial pulses of prostaglandin F2alpha for complete physiologic leteolysis in cattle. Biology of Reprouction, v.80, p.641-648, 2009.
Goel, A.K.; Agrawal, K.P. Oestrus synchronization in cyclic goats following lutalyse administration. Indian Journal of Animal Science, v.68, p.155- 156, 1998.
González de Bulnes, A.; Moreno, S.; Gómez-Brunet, A. et al. Follicular dynamic during the oestrous cycle in dairy goats. Animal Science, v.68, p.547- 554, 1999.
González de Bulnes, A.; Veiga-López, A.; García, P. et al. Effects of progestagens and prostaglandin analogues on ovarían function and embryo viability in sheep. Theriogenology, v.63, p.2523- 2534, 2005.
González-Añover, P.; Encinas, T.; Veiga-López, A. et al. Effects of bree don folicular dynamics and oestradiol secretion during the folicular phase in sheep. Reproduction Domestic Animal, v.42, p.29-33, 2007.
Goravanahally, M.P.; Sen, A.; Inskeep, E.K., et al. PKCepsilon and an increase in intracellular calcium concentration are necessary for PGF2alpha to inhibit LH-stimulated progesterone secretion in cultured bovine steroidogenic luteal cells. Reproductive Biology and Endocrinology, v.5, p.1-13, 2007.
Guido, S.I.; Oliveira, M.A L.; Lima, P.F. Eficiência do syncromate-B associado a P F2 sobre o restablecimento da ciclicidade de cabras Saanen em anestro lactacional. Revista Brasileira de Reproducción Animal, v.23, p.51-56, 1999.
Hackett, A.J.; Robertson, H.A. Effect of dose and time of injection of prostaglandin F 2α in cycling ewes. Theriogenology, v. 13, p.347-351, 1980.
Herrera, H.L.; Feldman, S.D.; Zarco, Q.L. et al. Evaluación del efecto luteolítico de la prostaglandina F2 alfa en diferentes días del ciclo estral de la borrega. Veterinaria México, v. 21, p.143-147, 1990.
Holtz, W.; Sohnrey, B.; Gerland, M., et al. Ovsynch synchronization and fixed-time insemination in goats. Theriogenology, v. 69, p.785-792, 2008.
Kridli, R.T.; Al-Khetlib, S.S. Reproductive responses in ewes treated with eCG or increasing doses of royal jelly. Animal Reproduction Science, v.92, p.75-85, 2006.
Lafrance, M.; Goff, A. K. Effect of pregnancy on oxytocin-induced release of prostaglandin F2a in heifers. Biology of Reproduction, v.3, p.1113– 1119, 1985.
Latour, D.; Littell, R. Advanced general linear models with an emphasis on mixed models. Version 6.12. Cary: SAS Institute, 1996. 268p.
Leyva, V.; Buckrell, B.C.; WALTON, J.S. Regulation of follicular and ovulation in ewes by exogenous progestagen. Theriogenology, v.50, p.395-416, 1998.
Liu, X.; Dai, Q.; Hart, E.J. et al. Ultrasonographic characteristics of ovulatory follicles and associated endocrine changes in cyclic ewes treated with medroxyprogesterone acetate (MAP)-releasing intravaginal sponges and equine chorionic gonadotrophin (eCG). Reproduction Domestic Animals, v.42, p.393-401, 2007.
López-Sebastian, A.; González-Bulnes, A.; Carrizosa, J.A. et al. New estrus synchronization and artificial insemination protocol for goats based on male exposure, progesterone and cloprostenol during the non-breeding season. Theriogenology, v.68, p.1081-1087, 2007.
Lucy, M.C.; Savio, J.D.; Badinga, L. et al. Factors that affect ovarian follicular dynamics in cattle. Journal of Animal Science, v.70, p.3615-3626, 1992.
McGinley, R.; Casey, J. H. Analysis of progesterone in unextrated serum; a method using danazol (17 a-preg-4-en-20-yno (2,3) isoxasol-17-ol) a bloker of steroid binding to proteins. Steroids, v.33, p.127-138, 1979.
McNeilly, A.S.; Picton, H.M.; Campbell, B.K. et al. Gonadotrofic control of follicle growth in the ewe. Journal of Reproduction and Fertility, v.43, p.177-186, 1991.
Menchaca, A.& Rubianes, E. Efecto of high progesterone concentrations during the early luteal phase in the lenght of the ovulatory cycle of gotas. Animal Reproduction Science, v.68, p.69-76, 2001.
Menchaca, A. & Rubianes, E. Relation between progesterone concentrations during the early luteal phase and follicular dynamic in goats. Theriogenology, v.57, p.1411-1419, 2002.
Menchaca, A.; Miller, V.; Salveraglio, V. et al. Endocrine, luteal and folicular responses after the use of the short-term protocol to synchronize ovulation in goats. Animal Reproduction Science, v.102, p.76-87, 2007.
Mihm, M.; Curran, N.; Hyttel, P. et al. Effect of dominant follicle persistence on follicular fluid estradiol and inhibin and on oocyte maturation in heifers. Journal of Reproduction and Fertility, v.116, p.293-304, 1999.
Pierson, R.A.; Ginther, J.O. Follicular population during the oestrous cycle in heifers. I – Influence of day. Animal Reproduction Science, v.14, p.165-176, 1987.
Quirk, S.M.; Quirk, G.J.; Hickey, J.E. et al. Growth and regression of ovarian follicles during the follicular phase of the oestrous cycle in heifers undergoing spontaneous and PGF2α induced luteolysis. Journal Reproduction of Fertility, v.77, p.211-219, 1986.
Ravindra, J.P.; Rawlings, N.C.; Evans, A.C.O. et al. Ultrasonographic study of ovarian follicular dynamics in ewes during the estrous cycle. Journal Reproduction and Fertility, v.101, p.501-509, 1994.
Safdarian, M.; Kafi, M.; Hashemi, M. Reproductive performance of Karakul ewes following different oestrous synchronization treatments outside the natural breeding season. South African Journal of Animal Sciences, v.36, p.229-234, 2006.
Scaramuzzi, R.J.; Adams, N.R.; Baird, D.T. et al. A model for follicle selection and the determination of ovulation rate in the ewe. Reproduction Fertility Development, v.5, p.459-478, 1993.
Schrick, F.N.; Surface, R.A.; Pritchard, J.Y. et al. Ovarian structures during the estrous cycle and early pregnancy in ewes. Biology of Reproduction, v.49, p.1133-1140, 1993.
Uribe-Velásquez, L.F.; Oba, E.; Lara-Herrera, L.C.; et al. Respostas endócrinas e ovarianas associadas com o folículo dominante da primeira onda folicular em ovelhas sincronizadas com CIDR ou PGF2α. Revista Brasileira de Zootecnia, v.31, p.944-953, 2002.
Uribe-Velásquez, L.F.; Souza, M.I.L.; Loaiza, A.M.E. Efecto de la sincronización del estro con prostaglandina-f2α vs CIDR + 500 UI de eCG en ovejas Bergamacia durante el inicio de la fase luteal. Revista Científica, v.XVIII, p.368-373, 2008a.
Uribe-Velásquez, L.F.; Oba, E.; Souza, M.I.L. Población folicular y concentraciones plasmáticas de progesterona (P4) en ovejas sometidas a diferentes protocolos de sincronización. Archivos de Medicina Veterinaria, v.40, p.83-88, 2008b.
Uribe-Velásquez, L.F.; Oba, E.; Souza, M.I.L. Efeitos da progesterona exógena sobre o desenvolvimento folicular em ovelhas. Arquivos Brasileiros de Medicina Veterinária e Zootecnia, v.60, p.58- 65, 2008c.
Weems, C.W.; Weems, Y.S.; Randel, R.D. Prostaglandins and reproduction in female farm animals. The Veterinary Journal, v. 171, p.206- 228, 2006.
Descargas
Los datos de descargas todavía no están disponibles.
