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Publication Date: 2010-12-17
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Aristizábal Arbeláez, M. ., Osorio Morales, L. ., & Pedraza Ordóñez, F. . (2010). Immunophenotyping of canine lymphoma and relationship with clinical prognosis. Revista Veterinaria Y Zootecnia (On Line), 4(2), 23–29. Retrieved from https://revistasojs.ucaldas.edu.co/index.php/vetzootec/article/view/5594
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Abstract
ABSTRACT: Canine lymphoma has been a useful animal model for non-Hodgkin’s lymphomas in humans. Five cases of malignant lymphoma (lymphosarcoma) in dogs that died due to illness are accounted for in this study. The cases were immuno-labeled using monoclonal and polyclonal antibodies against surface antigens of T and B Lymphoid cells in order to attempt the neoplasias classification and to establish prognostic parameters around this cellular characteristic. Two cases were classified as originating from T cells and no one in the B cells. The possibility of using immunohistochemistry in future cases where prognostic criteria and treatment in patients affected by canine lymphoma can be established is discussed.
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References
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Vail, D.M.; Thamm, D.H.; Reiser, H. et al. Assessment of GS-9219 in a pet dog model of non-Hodgkin’s lymphoma. Clinical Cancer Research, v.15, p.3503-3510, 2009.
Vernau, W.; Moore, P.F. An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction. Veterinary Immunology Immunopathology, v.69, p.145-164, 1999.
Vezzali, E.; Parodi, A.L.; Marcato, P.S.; Bettini, G. Histopathologic classification of 171 cases of canine and feline non-Hodgkin lymphoma according to the WHO. Veterinary and Comparative Oncology, v.8, p.38-49, 2010.
Madrid, España: Interamericana - McGrawHill, 1999. p.71-101. Alizadeh, A.A.; Eisen, M.B.; Davis, R.E. et al.
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature, v.403, p.503-511, 2000.
Álvarez-Berger, F.J.; Fernández, E.A.; Aristi-Urista, G.; Chávez-Gris, G. Estudio histológico e inmunofenotípico de linfoma canino en el centro de México. Veterinaria México, v.40, n.2, p.141-155, 2009.
Arespacochaga, G.; Schwendenwein, I.; H. Weissenbock. Retrospective Study of 82 Cases of Canine Lymphoma in Austria based on the Working Formulation and Immunophenotyping. Journal Comparative Pathology, v.136, p.186-192, 2007.
Chuaqui, B.J.; González, B.S.; editores. Tumores de tejidos linforreticulares y hematopoyéticos. En: Manual de Patología general. Pontificia Universidad Católica de Chile, 20011.
Disponible en: http://escuela.med.puc.cl/publ/ patologiageneral/patol_099.html Accesado en: 15/02/2011.
Dobson, J.M.; Blackwood, L.B.; Mcinnes, E.F. et al. Prognostic Variables in Canine Multicentric Lymphosarcoma. Journal Small Animal Practice, v.42, p.377-384, 2001.
Fournel-Fleury, C.; Magnol, J.P.; Bricaire, T. Cytohistological and immunological classification of canine malignant lymphomas: comparison with human non-Hodgkin’s lymphomas. Journal of Comparative Pathology, v.117, p.35-59, 1997.
Garrett, L.D.; Thamm, D.H.; Chun, R. et al. Evaluation of a 6-month chemotherapy protocol with no maintenance therapy for dogs with lymphoma. Journal of Veterinary Internal Medicine, v.16, p.704-709, 2002.
Gavazza, A.; Lubas, G.; Valori, E.; Gugliucci, B. Retrospective surrey of malignant lymphoma cases in the dog: clinical, therapeutical and prognostic features. Veterinary Research Communications, v.32, p.291-293, 2008 (suppl.1).
Greenlee, P.G.; Filippa, D.A.; Quimby, F.W. et al. Lymphomas in dogs. A morphologic, immunologic, and clinical study. Cancer, v.66, p.480-490, 1990.
Hosoya, K.; Kisseberth, W.C.; Lord, L.K. Comparison of COAP and UW-19 protocols for dogs with multicentric lymphoma. Journal of Veterinary Internal Medicine, v.21, p.1355-1363, 2007.
Jacobs, R.M.; Messick, J.B.; Valli, V.E. Tumors of the hemolymphatic system, Tumors of domestic animals. 4.ed., Iowa, USA: State Press, 2002. 138p.
Jamadar-Shroff, V.; Papich, M.G.; Suter, S.E. Soyderived isoflavones inhibit the growth of canine lymphoid cell lines. Clinical Cancer Research, v.15, p.1269-1276, 2009.
Kaiser, H.E.; editor. Animal neoplasms: a systemic review. Neoplasms. Comparative Pathology in Animals, Plants and Man. Baltimore, USA: Williams and Wilkins, 1981. p.747-812.
MacEwen, E.G.; Hayes, A.A.; Matus, R.E.; Kurzman, I. Evaluation of some prognostic factors for advanced multicentric lymphosarcoma in the dog: 147 cases (1978-1981). Journal of the American Veterinary Medical Association, v.190, p.564-568, 1987.
Miller, A.G.; Morley, P.S.; Rao, S. et al. Anemia is associated with decreased survival time in dogs with lymphoma. Journal of Veterinary Internal Medicine, v.23, p.116-122, 2009.
Pedraza, F.J.; Schild, A.L.; Alessi, A.C. Immunohistochemical description of encephalitis in Brazilian cattle naturally infected with bovine herpes virus type 5 (BoHV5). Archivos de Medicina Veterinaria, v.40, p.69-75, 2008.
Ponce, F.; Marchal, J.P.; Magnol, V. et al. A morphologic study of 608 cases of canine malignant lymphoma in France with a focus on comparative similarities between canine and human lymphoma morphology. Veterinary Pathology, v.47, p.414-433, 2010.
Sapierzyński, R. Practical aspects of immunocytochemistry in canine lymphomas. Polish Journal of Veterinary Sciences, v.13, n.4, p.661-668, 2010.
Thomas, R.; Smith, K.C.; Gould, R. et al. Molecular Cytogenetic Analysis of a novel Highgrade Canine T-Lymphoblastic Lymphoma Demonstrating Co-expression of CD3 and CD79a Cell Markers. Chromosome Res, v.9, n.8, p.649-657, 2001.
Tranah, G.J.; Bracci, P.M.; Holly, E.A. Domestic and Farm-Animal exposures and risk of NonHodkin´s lymphoma in a population based study in the San Francisco Bay Area. Cancer epidemiology biomarkers prevention, v.17 n.9, 2008.
Uppenkamp, M.; Feller, A.C. Classification of malignant lymphoma. Onkologie, v.25, p.563- 570, 2002.
Vail, D.M.; Thamm, D.H.; Reiser, H. et al. Assessment of GS-9219 in a pet dog model of non-Hodgkin’s lymphoma. Clinical Cancer Research, v.15, p.3503-3510, 2009.
Vernau, W.; Moore, P.F. An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction. Veterinary Immunology Immunopathology, v.69, p.145-164, 1999.
Vezzali, E.; Parodi, A.L.; Marcato, P.S.; Bettini, G. Histopathologic classification of 171 cases of canine and feline non-Hodgkin lymphoma according to the WHO. Veterinary and Comparative Oncology, v.8, p.38-49, 2010.
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