Authors
Abstract
Since the beginning of the field technological development, the livestock production target has been the improvement of the systems through resources optimization to achieve high production levels. Not all of the biological components of such systems, respond the same way to offered nutrients, it is due largely to its genetic component. In response to this situation has emerged an useful tool that could be implemented and applied to daily management of milk production systems in the country. This tool is the genetic improvement through molecular manipulation or molecular assisted selection (MAS) markers. This research target was to determine the genetic structure of a Holstein population in Antioquia by the use of polymorphism 292 C>T from the factor gene of insulin-like growth type 2 (IGF2a). A population of 1054 animals of the Holstein breed, distributed in 6 subpopulations was evaluated in Antioquia. Genotyping was performed using PCR-RFLP technique. The Genalex6 and Arlequin 3.5 software were used to determine the statistical F Wright, the Hardy-Weinberg equilibrium and Nei distances. Allele frequencies for the 292 polymorphism C>T of IGF2a were T (0.405) and C (0.595). The total population was in Hardy – Weinberg balance, however El Retiro subpopulation was unbalanced. The genetic structure of the population showed low differentiation between all studied subpopulations, where the FST was 0.002. In addition, there were found levels of 0.263 Fit and levels of 0.261 Fis rated in the lower ranges described by Wright.
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