Comparación del perfil lipídico y del perfil tiroideo en caninos adultos obesos vs caninos adultos normales

Abstract

The energy and thyroid metabolism were studied in obese adult canine vs. normal adult canine. Fasting serum from 80 adult canines was obtained (40 obese canines older than one year and 40 normal canines older than one year). The levels of thyrotropin (TSH) and free thyroxine (T4L) were determined by enzyme immunoassay. The total cholesterol (TC), triglycerides (TAG) and HDL cholesterol (HDL-C) values were determined by enzymatic-colorimetric methods. The levels of LDL cholesterol (LDL-C) were obtained by the direct method and those of VLDL cholesterol (VLDL-C) were obtained with the Friedewald formula (TAG/5). The mean values of TSH (μUI/ml), T4L (ng/dl), CT (mg/dl), TAG (mg/dl), HDL-C and LDL-C (mg/dl) for obese adult canines were: 1.04; 1.05; 242.44; 58.82; 162.9; 11.75; 71.68, respectively. For the normal adult canines, the mean values were: 1.27; 0.93; 201.49; 37.57; 134.94; 7.42; 49.34, respectively. No significant difference was found in the levels of TSH and T4L in adult obese canines vs. normal adult canines (P-value: 0.51; 0.26, respectively). A significant difference was observed for the lipid profile. No significant difference was observed when comparing male/female canines with 95% reliability. In conclusion, the lipid profile is clearly altered in obese canines. Regarding the thyroid profile, no significant differences were found, although some author mention that fatty tissue affects this profile.

Keywords:

metabolismo

canino

tirotropina

tiroxina libre

lípidos

metabolism

canine

thyrotropin

free thyroxine

lipids

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